This course will include basics of protein chemistry, concepts and theories of protein folding, protein folding problem (PFP) and diseases it can cause, predicting protein folding and related bioinformatics, details about molten globule of protein conformation, intrinsically disorder proteins (IDPs) and their functional impact, Bio analytical techniques to study protein conformation, Introduction of toxin and their different conformations and functions, and evolution of proteins including protein toxins.